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Telling apart psoriasis and eczema

Photo of a patient’s skin who has psoriasis plaques in the center and eczema around the plaques. Photo courtesy of Kilian Eyerich. Eczema and psoriasis are chronic inflammatory skin diseases that...

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Thalidomide’s molecular actions revealed

Once shunned for causing severe birth defects in babies, thalidomide has made a comeback to treat some blood cancers and leprosy. In a paper now out in Nature, researchers describe the crystal...

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On the hook: A new pipette to capture single cells

The handheld single-cell pipette. Image provided by Lidong Qin. Seeking out individuals from a crowd has become increasingly important for biologists interested in single-cell analyses. Studies on...

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How a squid forms a relationship with a bacterium

The Hawaiian bobtail squid forms a symbiotic relationship with a bioluminescent bacterium. Photo provided by Spencer Nyholm. How do you get into a mutually beneficial relationship? That is the question...

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Model to explain cellular sensor organization

  A new model proposes a general organizing principle for sensors on cells. Image from http://en.wikipedia.org/wiki/Cell_(biology)#mediaviewer/File:DAPIMitoTrackerRedAlexaFluor488BPAE.jpg...

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Surviving in the Pacific Ocean, bacterial style

Scientists collected samples during a research cruise in October 2011 along a 2,500-mile stretch in the Pacific Ocean, from Hawaii to Samoa. [Credit: Brian Dimento, University of Connecticut]Oceans...

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A mouse model for childhood obesity

  Images of fetal and adult human adipose tissue grafted onto kidneys of immunodeficient mice. Photos were taken at the time of explantation at 14, 30 and 60 daysafter transplantation. Yellow arrows...

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Sharing my byline and other adventures in punk rock

I gingerly slid the disc into my car CD player and braced myself against the steering wheel for the anticipated onslaught of noise. Instead, a voice, rich and smooth like molten chocolate, began to...

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Synchronizing mitochondrial metabolism

Watching mitochondria go through waves of ATP production. Image by Roberto Weigert and Natalie Porat-Shliom. Mitochondria are fidgeters. That’s what researchers discovered in a recent study. The...

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How a plant molecule is a “superb” sunscreen

    Plants make their own sunblock to protect against UV damage. Image from http://en.wikipedia.org/wiki/Plant#mediaviewer/File:Leaf_1_web.jpg Like us, plants worry about sunburn. Research now shows...

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Researchers culture norovirus

A working model for norovirus infection of the intestine. Noroviruses bind specific carbohydrates on commensal bacteria (histo-blood group antigens [HBGA]) in the gut lumen; the virus:bacteria complex...

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From country girl to author on most cited paper: Nira Rosebrough Roberts

Nira Rosebrough Roberts. Photo provided by Lauren Buendia. “I was a little country girl who really didn’t know much of anything. But I was very good at what I did and we made a good team.” That is Nira...

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Fishing out the proteomic changes in salmon exposed to drugs

Researchers looked at how pharmaceuticals in water affected protein expression in the livers of Atlantic salmon. Photo provided by Miriam Hampel. Pharmaceutical compounds in waterways have become a...

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National Academies report urges higher salaries and better training for...

The National Academies released a report today that advocates for improvements in training and salary for postdoctoral fellows in academia. Although postdoctoral training is necessary to pursue careers...

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Making the complex less complicated: Scientists create a simple, functional...

Researchers report the computational design, structure, and function of a transmembrane protein. (Artwork conceived and produced by Nathan Joh) Scientists have designed a stripped-down version of a...

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Disease detection on a dongle

A smartphone dongle with a disposable microfluidic cassette.[Credit: Tassaneewan Laksanasopin]A handheld device powered by a smartphone can diagnose HIV and syphilis in Rwanda. In a paper just out in...

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Boar semen biomarkers predict litter size

Researchers found biomarkers that can predict pig litter sizes. Photo by GregManninLB – Transferred from en.wikipedia.org [1]: 2008-03-24 20:37. Licensed under Public Domain via Wikimedia CommonsPig...

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Why high-fat, low-carb diets help some epileptics

A series of pie charts depicting the calorific contributions from carbohydrate, protein and fat in four diets: the typical American diet; the Atkins diet during the induction phase; the classic...

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Mitochondrial replacement therapy: Critical treatment or risky business?

Mitochondrial replacement therapy to stop the transmission of mitochondrial disease involves the transfer of nuclear DNA from an affected egg to a donor egg with healthy mitochondria.Credit: Australian...

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Blood for all: Making universal blood through enzymes

Making universal blood. Image provided by Stephen Withers and David Kwan. Universal blood is an appealing notion because it could be transfused into anyone regardless of blood type. Researchers have...

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